It is a title of a paper published today Current medical research and opinion Co-writers with Nadin Zavadzki, Moiz Marin, Ivana Audahya, Lauren Sedita, Natasha Kulkarni and Alexa Climachak. The essence is below.
Objective
Duchene muscular dystrophy (DMD) determine the risk preferences that affect time that affects time that affects time.
Methods
DMD patients were surveyed (medical decision-makers) to evaluate their preferences in 2 remedies over time with the same (average) time as the Loa: with 1 variable (ie longer than average or less) time for Lo and fixed with 1 for Loa and 1 with 1 variable. The time was changed to the Loa with certain therapy to determine the career’s apathy point. The study closing point (i) was the share of carers who preferred variables (vs certain) time for Loa therapy; And (ii) Loa to the length of fixed time that will result in the concerning indifference between variables and fixed treatments, calculated using parameter estimates by sequential testing. The base case examined the medical choice for DMD patient, a fictional ambulance of 9 years of age; Sensitivity analysis detected preferences for young (age of 5 years) and older (age 13) patients.
Result
Among the 103 carers involved in the survey, 72 (69.9%) preferred variable time for LOA therapy for a fictional 9 -year -old patient with DMD (P<0.001). Careful was ready to give 11.5 months (PFor a long time for a long time for Loa <0.001). The preference of care for variable therapy decreased with the age of the imaginary patient in initiation of treatment, for the age of 72.8% (75/103) to the age of 5 years (P<0.001) 60.2% (62/103) for the age of 13 years (62/103) (P= 0.048).
conclusion
Patients with DMD performed risk tolerance (positive value of hope) for the treatments that could delay the LOA.
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